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We approach to start a cohort of MCLA-129 together with chemotherapy in 2L+ EGFRm NSCLC in the 1st quarter of upcoming 12 months. In addition, we remain fascinated and so are continuing investigation of cohort B evaluating MCLA-129 in patients with MET exon14 skipping NSCLC. We also stay serious about Checking out partnering MCLA-129 with other businesses to adequately source the development of MCLA-129 and opportunity gain it could have for patients.

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Our assessment of the cohort would be that the scientific exercise of MCLA-129 in next line head and neck cancer appears significantly inferior to that of our guide asset petosemtamab, and only this page on par with other EGFR or cetuximab-centered monoclonal or bispecific antibodies as monotherapy in an analogous location. We consider this efficacy is inadequate to warrant even further enhancement in head and neck most cancers.

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